firc institute of molecular oncology

Nicoletta Guaragnella

Nicoletta Guaragnella

Research associate at National Research Council-Institute of Biomembranes and Bioenergetics (CNR-IBBE) in Bari

Nicoletta Guaragnella has a permanent position as a research associate at National Research Council-Institute of Biomembranes and Bioenergetics (CNR-IBBE) in Bari (Italy) since 2010. Her major scientific interests are: pro-survival and pro-death signaling in cell stress response; mitochondria to nucleus communication, known as mitochondrial retrograde signaling and heterologous expression of human oncosuppressors, such as BRCA2 (Breast Cancer Susceptibility gene), in the model organism yeast Saccharomyces cerevisiae. She is now expanding her scientific experience working on the molecular mechanisms of cell stress response in wild yeast used for biotechnological applications. During her PhD in Biochemistry and Molecular Biology, she was trained as a junior fellowship in the laboratory of Ronald Butow in Dallas at University of Texas, Southwestern Medical School. In 2013 she has been visiting scientist in Valter Longo' laboratory and worked on the relations between sir2 and apoptosis in yeast aging cells. At CNR-IBBE she is also involved in mentoring programs for undergraduate students and is responsible for the activities of scientific communication and dissemination. She coordinates the organization of public events for scientific dissemination and actively collaborates with CNR Press Office in Rome, Almanacco della Scienza, Scienza in Rete, Rivista dell'Ordine Nazionale dei Biologi.

Guaragnella's article

March 2015

Regeneration of Hematopoietic Stem Cells and immunosuppression recovery: the power of prolonged fasting

Commentary on Valter Longo's paper published on Cell Stem Cell.